[Gasification] Methanol toxicity?

Thomas Reed tombreed at comcast.net
Mon Jul 3 09:49:21 CDT 2006


Dear Thomas:

Right on! 

Methanol does not corrode aluminum, but will do a job on magnesium.  So 
in testifying in Congress against methanol (and me) in 1975, Chevron 
showed the magnesium tank of a chain saw to show that methanol would not 
be a practical fuel. 

I hope we're not too late to start serious alternate fuels.

TOM REED     BEF

Thomas Pirotte wrote:
> I have never seen or heard of any instance of CH3OH absorption through the skin, from a "splash" exposure, causing any significant toxicity.  I used methanol plenty of times back on Organic Chemistry lab...
>
> I read a blurb containing the factoid "methanol corrodes aluminum fittings."  Any truth?
>
> T. Pirotte, M.D.
>
> -----Original Message-----
> From: bioconversion-bounces at listserv.repp.org
> [mailto:bioconversion-bounces at listserv.repp.org]On Behalf Of Thomas Reed
> Sent: Thursday, June 29, 2006 08:14
> To: Dick Glick
> Cc: bioconversion at listserv.repp.org; Gasification
> Subject: [Bioconversion] Methanol toxicity
>
>
> Dear Glick and All:
>
> There is a lot of misinformation about methanol toxicity around, partly 
> because the oil companies were dedicated to making sure it didn't 
> compete with petroleum starting with our work in 1973.  (See details at 
> http://www.woodgas.com/methanol.htm).
> ------------------------------------------------------------------------
>
> According to my Merck handbook the usual fatal dose for *methanol *is 
> 100-250 ml, but less than 30 ml has been reported.  On *ethyl alcohol* 
> they report "Nausea, vomiting, flushing, mental excitement or 
> depression, drowsiness, impaired perception, incoordination, stupor, 
> coma, death may occur."  I believe there are over 100,000 deaths 
> attributed to ethanol in the US each year, and for methanol less than 10 
> worldwide, even though methanol production exceeds ethanol (?).   
> (Methanol is also an intermediate for plastics, etc.)
>
> Shortly after I began my "methanol as an additive and the eventual 
> replacement for gasoline" campaign in 1973 I got good advice on the 
> toxicology from a Canadian physician. 
>
> Most methyl alcohol toxic events were caused by confusing it with ethyl 
> alcohol, so we decided that "methanol" was a better name than "methyl 
> alcohol" or "wood alcohol".  Painters were famous for drinking a wide 
> variety of alcohols and were paraticularly susceptible around the turn 
> of the century.  Sailors likewise. 
>
> Many liquors can contain methanol and I remember that Schlivovitz had 4%. 
>
> The mechanism of methanol poisoning is that the ethanol dehydrogenaze in 
> your stomach thinks it is ethanol and decomposes it to formic acid, 
> definitely stronger than acetic acid and can cause blindness and death.  
> A second mechanism is that methanol is not as intoxicating as ethanol, 
> and so a dedicated drunk will keep on drinking it, waiting for bliss, 
> rather than oblivion.  The recommended antidote for accidentally 
> drinking methanol is a dose of whiskey.  This gives the dehydrogenaze 
> the proper food to work on and the methanol passes through with less harm. 
>
> The toxicity of methanol is a blessing in disguise.  Ethanol is easily 
> diverted into the home brew beverage category.  Methanol won't be.  
> Methanol is very biodegradable in the environment.  It is much less 
> toxic than gasoline. 
>
> So, let's get on with methanol as the simplest replacement for gasoline 
> and don't even think about it as a beverage. 
>
> Your realistic fuel chemist,
>
> TOM REED   The Biomass Energy Foundation
>
>
> Dick Glick wrote:
>   
>> Hello All --
>> I don't know how I lived through 60 years in the chemistry lab -- all 
>> those horrible solvents like methanol, benzene, toluene, etc -- but 
>> times have changed and now they're killers -- ???
>>
>> Best, Dick
>> www.CorpFutRes.com
>>
>>
>>
>> ----- Original Message ----- From: "Harmon Seaver" <hseaver at gmail.com>
>> To: "Gasification" <GASIFICATION at listserv.repp.org>; 
>> <bioconversion at listserv.repp.org>
>> Sent: Tuesday, June 27, 2006 9:23 AM
>> Subject: Re: County wide methanol project -- was: Re: [Gasification] 
>> Re:Gasification Digest, Vol 23, Issue 28
>>
>>
>>     
>>> Just do a google on methanol toxicity. For instance:
>>>
>>> "Lethal doses are thought to range from 30-240 mL; the minimum lethal
>>> dose is believed to be 1 g/kg body weight."
>>>
>>> http://www.emedicine.com/NEURO/topic217.htm
>>>
>>>   Methanol is very readily absorbed thru the skin, sub-lethal doses
>>> cause damage to the nervous system and eyes.
>>>
>>>
>>>
>>> On 6/26/06, Arnt Karlsen <arnt at c2i.net> wrote:
>>>       
>>>> On Mon, 26 Jun 2006 19:48:22 -0500, Harmon wrote in message
>>>> <22acb24d0606261748i7c237c34v507d837d9d18cd5a at mail.gmail.com>:
>>>>
>>>>         
>>>>>    This conversation really belongs on the bioconversion list rather
>>>>> than gasification.
>>>>>           
>>>> ..aye.
>>>>
>>>>         
>>>>> But have you given any thought to just how toxic methanol is? 
>>>>>           
>>>> Spill it
>>>>         
>>>>> on your hand while refueling and you probably won't survive the
>>>>> experience.
>>>>>           
>>>> ..maybe I'm on long term bonus time, but some aero modellers have 
>>>> messed
>>>> around with methanol and castor oil for decades.  We do however worry
>>>> about epoxy glues and paints, there is an individual and appearantly
>>>> accumulating tolerance limit, some oldtimers can mess around for 
>>>> decades
>>>> with no visible effects while a few unfortunate souls lose their health
>>>> building their first model.
>>>>
>>>> -- 
>>>> ..med vennlig hilsen = with Kind Regards from Arnt... ;o)
>>>> ...with a number of polar bear hunters in his ancestry...
>>>>   Scenarios always come in sets of three:
>>>>   best case, worst case, and just in case.
>>>>
>>>> _______________________________________________
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>>>>
>>>>         
>>> -- 
>>> Harmon Seaver
>>> _______________________________________________
>>> Gasification mailing list
>>> Gasification at listserv.repp.org
>>> http://listserv.repp.org/mailman/listinfo/gasification
>>> http://www.repp.org/discussiongroups/resources/gasification 
>>>       
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>>
>>     
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